Famous for his roles as Manny Beltran and Vic Palermo in the respective situation comedies Los Beltran (on the Telemundo network) and George Lopez (on ABC), Diez is also notable for his guest star roles on the CBS sitcom Everybody Loves Raymond and on the NBC soap opera Passions. His early acting credits include performances in Florida theatrical productions of La Cage Aux Folles and Blithe Spirit.